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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
O75821
USC-OGP 2-DE database
:
O75821
O75821
General information about the entry
View entry in simple text format
Entry name
EIF3G_HUMAN
Primary accession number
O75821
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Eukaryotic translation initiation factor 3 subunit G {ECO:0000255|HAMAP-Rule:MF_03006}; Short=eIF3g {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=Eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255|HAMAP-Rule:MF_03006}; Short=eIF-3 RNA-binding subunit {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF-3-delta {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF3 p42 {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF3 p44 {ECO:0000255|HAMAP-Rule:MF_03006};.
Gene name
Name=EIF3G
{ECO:0000255|HAMAP-Rule:MF_03006}
Synonyms=EIF3S4 {ECO:0000255|HAMAP-Rule:MF_03006}
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1176
:
pI=5.57; Mw=44777
SPOT OGP-1182
:
pI=6.10; Mw=44152
Cross-references
UniProtKB/Swiss-Prot
O75821; EIF3G_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
EIF3G_HUMAN
Primary accession number
O75821
Secondary accession number(s)
O14801 Q969U5
Sequence was last modified on
September 19, 2002 (version 2)
Annotations were last modified on
March 15, 2017 (version 174)
Name and origin of the protein
Description
RecName: Full=Eukaryotic translation initiation factor 3 subunit G {ECO:0000255|HAMAP-Rule:MF_03006}; Short=eIF3g {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=Eukaryotic translation initiation factor 3 RNA-binding subunit {ECO:0000255|HAMAP-Rule:MF_03006}; Short=eIF-3 RNA-binding subunit {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 4 {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF-3-delta {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF3 p42 {ECO:0000255|HAMAP-Rule:MF_03006}; AltName: Full=eIF3 p44 {ECO:0000255|HAMAP-Rule:MF_03006};
Gene name
Name=EIF3G
{ECO:0000255|HAMAP-Rule:MF_03006}
Synonyms=EIF3S4 {ECO:0000255|HAMAP-Rule:MF_03006}
Encoded on
Name=EIF3G {ECO:0000255|HAMAP-Rule:MF_03006}; Synonyms=EIF3S4 {ECO:0000255|HAMAP-Rule:MF_03006
Keywords
3D-structure
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Initiation factor
;
Nucleus
;
Phosphoprotein
;
Protein biosynthesis
;
Reference proteome
;
RNA-binding
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U96074; AAC78728.1
; -; mRNA
EMBL
AF020833; AAB71866.1
; -; mRNA
EMBL
AF092453; AAG15396.1
; -; Genomic_DNA
EMBL
AF094850; AAG15419.1
; -; mRNA
EMBL
BT006889; AAP35535.1
; -; mRNA
EMBL
BC000733; AAH00733.1
; -; mRNA
EMBL
BC008469; AAH08469.1
; -; mRNA
CCDS
CCDS12227.1; -
; .
RefSeq
NP_003746.2; NM_003755.4
; .
UniGene
Hs.529059; -
; .
PDB
2CQ0; NMR
; -; A=231-320
PDB
2MJC; NMR
; -; A=150-179
PDB
5K0Y; EM
; 5.80 A; M=103-140
O=239-315
PDBsum; 2CQ0; -; .
PDBsum
2MJC; -
; .
PDBsum
5K0Y; -
; .
ProteinModelPortal
O75821; -
; .
SMR
O75821; -
; .
BioGrid
114215; 57
; .
DIP
DIP-31115N; -
; .
IntAct
O75821; 38
; .
MINT
MINT-3001737; -
; .
STRING
9606.ENSP00000253108; -
; .
iPTMnet
O75821; -
; .
PhosphoSitePlus
O75821; -
; .
SwissPalm
O75821; -
; .
BioMuta
EIF3G; -
; .
EPD
O75821; -
; .
MaxQB
O75821; -
; .
PaxDb
O75821; -
; .
PeptideAtlas
O75821; -
; .
PRIDE
O75821; -
; .
TopDownProteomics
O75821; -
; .
DNASU
8666; -
; .
Ensembl
ENST00000253108; ENSP00000253108
; ENSG00000130811; .
GeneID
8666; -
; .
KEGG
hsa:8666; -
; .
UCSC
uc002mnd.4; human
; .
CTD
8666; -
; .
GeneCards
EIF3G; -
; .
HGNC
HGNC:3274; EIF3G
; .
HPA
HPA041997; -
; .
MIM
603913; gene
; .
neXtProt
NX_O75821; -
; .
OpenTargets
ENSG00000130811; -
; .
PharmGKB
PA162384827; -
; .
eggNOG
KOG0122; Eukaryota
; .
eggNOG
ENOG410Y3CW; LUCA
; .
GeneTree
ENSGT00510000047802; -
; .
HOGENOM
HOG000239560; -
; .
HOVERGEN
HBG026850; -
; .
InParanoid
O75821; -
; .
KO
K03248; -
; .
OMA
IVRTYKI; -
; .
OrthoDB
EOG091G0GSV; -
; .
PhylomeDB
O75821; -
; .
TreeFam
TF101516; -
; .
Reactome
R-HSA-156827; L13a-mediated translational silencing of Ceruloplasmin expression
; .
Reactome
R-HSA-72649; Translation initiation complex formation
; .
Reactome
R-HSA-72689; Formation of a pool of free 40S subunits
; .
Reactome
R-HSA-72695; Formation of the ternary complex
; and subsequently; the 43S complex
Reactome
R-HSA-72702; Ribosomal scanning and start codon recognition
; .
Reactome
R-HSA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit
; .
ChiTaRS
EIF3G; human
; .
EvolutionaryTrace
O75821; -
; .
GeneWiki
EIF3G; -
; .
GenomeRNAi
8666; -
; .
PRO
PR:O75821; -
; .
Proteomes
UP000005640; Chromosome 19
; .
Bgee
ENSG00000130811; -
; .
CleanEx
HS_EIF3G; -
; .
ExpressionAtlas
O75821; baseline and differential
; .
Genevisible
O75821; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0005852; C:eukaryotic translation initiation factor 3 complex
; IDA:UniProtKB; .
GO
GO:0048471; C:perinuclear region of cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0000166; F:nucleotide binding
; IEA:InterPro; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0003743; F:translation initiation factor activity
; IEA:UniProtKB-KW; .
GO
GO:0006413; P:translational initiation
; IDA:UniProtKB; .
GO
GO:0075525; P:viral translational termination-reinitiation
; IDA:UniProtKB; .
CDD
cd12933; eIF3G
; 1; .
CDD
cd12408; RRM_eIF3G_like
; 1; .
Gene3D
3.30.70.330; -
; 1; .
HAMAP
MF_03006; eIF3g
; 1; .
InterPro
IPR017334; eIF3_g
; .
InterPro
IPR024675; eIF3g_N
; .
InterPro
IPR034240; eIF3G_RRM
; .
InterPro
IPR012677; Nucleotide-bd_a/b_plait
; .
InterPro
IPR000504; RRM_dom
; .
PANTHER
PTHR10352:SF4; PTHR10352:SF4
; 1; .
Pfam
PF12353; eIF3g
; 1; .
Pfam
PF00076; RRM_1
; 1; .
PIRSF
PIRSF037949; Transl_init_eIF-3_RNA-bind
; 1; .
SMART
SM00360; RRM
; 1; .
SUPFAM
SSF54928; SSF54928
; 1; .
PROSITE
PS50102; RRM
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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